Cytoplasmic retention
WebApr 1, 2006 · Nucleo-cytoplasmic distribution of β-catenin is regulated by retention. J Cell Sci (2006) 119 (7): 1453–1463. β-catenin is the central signalling molecule of the … WebJun 6, 2014 · The results introduce a new paradigm where cytokine treatment prolongs nuclear retention simultaneous with decreasing rather than increasing the rate of nuclear import. ... It would thus appear that the C-terminal tail of STAT3α contributes to cytoplasmic retention of STAT3 in the cytoplasm under basal conditions, with S727 within it helping ...
Cytoplasmic retention
Did you know?
WebOct 17, 2024 · This new understanding of the determinants of nuclear retention and cytoplasmic export provides a deeper understanding of how information flow is regulated in eukaryotic cells. Ultimately these processes promote the evolution of complexity in eukaryotes by shaping the genomic content through constructive neutral evolution. WebJan 1, 2005 · If the droplet is normally shed then its retention on sperm in the ejaculate may be associated with infertility, and there is considerable evidence that this is the case. …
WebNov 4, 2013 · Intron retention and cytoplasmic splicing are emerging forms of transcriptional regulation that add to the molecular diversity of mammalian cells. Evidence of the importance of nonnuclear transcript … WebThe cytoplasmic retention of the precursor molecule is controlled by a small region in its C-terminal part. We show that this region is responsible for the observed lack of DNA binding of the p50 precursor and controls the extent of …
WebFeb 15, 2024 · Nuclear/cytoplasmic fractionation showed that the SET modified by SUMO-1 was primarily distributed to the cytoplasm (Fig. 6c, e), whilst AAV2-SET-K68R was primarily retained in the nucleus (Fig. 6d, f), supporting that SET WT overexpression induces its SUMOylation and cytoplasmic retention. In the mouse hippocampus, the activity of … WebFeb 15, 2024 · Our findings suggest that SET SUMOylation stimulates its cytoplasmic retention and inhibits PP2A activity, consequently leading to tau hyperphosphorylation and cognitive impairments, which provides a new insight into the AD-like tau pathology. Keywords: Alzheimer’s disease; Cognitive impairments; PP2A; SET SUMOylation; Tau …
WebMar 21, 2024 · ERK-mediated Cytoplasmic Retention of USP11 Contributes to Breast Cancer Cell Proliferation by Stabilizing Cytoplasmic p21 Abstract. Breast cancer …
WebSpecialty. Immunology. Cytokine release syndrome ( CRS) is a form of systemic inflammatory response syndrome (SIRS) that can be triggered by a variety of factors … portland oregon moving and storageWebJan 21, 1997 · M-phase promoting factor or maturation promoting factor, a key regulator of the G 2 → M transition of the cell cycle, is a complex of cdc2 and a B-type cyclin. We have previously shown that Xenopus cyclin B1 has five sites of Ser phosphorylation, four of which map to a recently identified cytoplasmic retention signal (CRS). The CRS appears to … portland oregon multnomah county jailWebFeb 1, 2003 · Although predominantly cytoplasmic during interphase, this kinase complex translocates precipitously to the nucleus at the G 2-M transition. The interphase … portland oregon murders 2023Webdegradation [14, 17]. In contrast, the MAPK triggered linker phosphorylation of Smads in cytoplasm diminishes the receptor type I responsible Smad phosphorylation and favours the cytoplasmic retention and degradation of Smad. More information is provided in the main text.Note: Numbers in square brackets indicate relevant references included optimize cpu without overclockingWebNational Center for Biotechnology Information portland oregon naturopathic clinicWebMay 2, 2014 · Currently, it is known that in its inactive state, CAR is retained in the cytoplasm in a protein complex with HSP90 and the tetratricopeptide repeat protein cytosoplasmic CAR retention protein (CCRP). portland oregon mountain bike trailsWebAug 1, 1999 · The MA domain of these viruses contains a "cytoplasmic targeting and retention signal (CTRS)" which is necessary for the intracytoplasmic assembly of virus particles. 186, 190 A single amino acid ... portland oregon murder rate by year